Vinyl acetate or vinyl acetate monomer (VAM) is a versatile and economically important building block chemical used to manufacture polymers that have a wide variety of industrial and commercial applications.

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What’s New

Testing on the formation of acetaldehyde DNA adducts following exposure to inhaled vinyl acetate monomer vapors shows exogenous adduct formation is below endogenous background levels at concentrations under 200 ppm and non-detactable at concentrations under 10 ppm.

Read the papers by researchers from the University of North Carolina:

Yun-Chung Hsiao, Chih-Wei Liu, Gary Hoffman, Caroline Fang, Kun Lu. 2022.  Molecular Dosimetry of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer.  Toxicological Sciences, Volume 185, Issue 2, February 2022, Pages 197–207. (https://doi.org/10.1093/toxsci/kfab140).

 Chih-Wei Liu, Yun-Chung Hsiao, Gary Hoffman, and Kun Lu. 2021. LC–MS/MS Analysis of the Formation and Loss of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer through Inhalation. Chemical Research in Toxicology 2021 34 (3), 793-803. (DOI: 10.1021/acs.chemrestox.0c00404)